BDBM346561 (3-amino-1,1-dimethyl-propyl) 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate::US10202378, Example 165

SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)CCN)c(cn(C)c2=O)C#CC(C)(C)O

InChI Key InChIKey=PDSWSQHXOTYPBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346561   

LigandPNGBDBM346561((3-amino-1,1-dimethyl-propyl) 4-(3-hydroxy-3-methy...)
Affinity DataIC50: 21.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

LigandPNGBDBM346561((3-amino-1,1-dimethyl-propyl) 4-(3-hydroxy-3-methy...)
Affinity DataIC50: 551nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent