BDBM346450 US10202378, Example 63::ethyl 4-[2-(3-hydroxyphenyl)ethynyl]-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate

SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#Cc1cccc(O)c1

InChI Key InChIKey=NAHHKXZEHAYZJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346450   

LigandPNGBDBM346450(ethyl 4-[2-(3-hydroxyphenyl)ethynyl]-2,6-dimethyl-...)
Affinity DataIC50: 38.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346450(ethyl 4-[2-(3-hydroxyphenyl)ethynyl]-2,6-dimethyl-...)
Affinity DataIC50: 195nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent