BDBM346422 US10202378, Example 35::ethyl 4-(4-cyano-3-hydroxy-3-methyl-but-1-ynyl)-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate

SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)CC#N

InChI Key InChIKey=KFQOTUIOKFKYSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346422   

LigandPNGBDBM346422(ethyl 4-(4-cyano-3-hydroxy-3-methyl-but-1-ynyl)-2,...)
Affinity DataIC50: 100nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM346422(ethyl 4-(4-cyano-3-hydroxy-3-methyl-but-1-ynyl)-2,...)
Affinity DataIC50: 139nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
In DepthDetails
US Patent