BDBM34513 MLS000118887::N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(3-keto-4,6-dimethyl-isothiazolo[5,4-b]pyridin-2-yl)acetamide::N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3-oxidanylidene-[1,2]thiazolo[5,4-b]pyridin-2-yl)ethanamide::N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3-oxo-2-isothiazolo[5,4-b]pyridinyl)acetamide::N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)acetamide::SMR000095827::US9011882, Table 1, Compound 15::cid_5309169

SMILES COc1ccc(OC)c(CCNC(=O)Cn2sc3nc(C)cc(C)c3c2=O)c1

InChI Key InChIKey=RYJAPIBOQYMFQJ-UHFFFAOYSA-N

Data  4 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 34513   

TargetGag-Pol polyprotein(HIV-1)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataIC50: 3.08E+3nMpH: 8.0 T: 2°CAssay Description:A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataEC50:  4.06E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataEC50:  1.21E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataEC50:  1.76E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataEC50:  4.65E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataEC50:  6.58E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataIC50: 5.66E+3nMAssay Description:Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetLarge T antigen(SV40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataIC50: 2.21E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataIC50: 9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails
US Patent