BDBM34438 1-{[6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-1H-1,2,3-benzotriazole::3-(1-benzotriazolylmethyl)-6-(2,3-dihydro-1,4-benzodioxin-3-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::3-(benzotriazol-1-ylmethyl)-6-(2,3-dihydro-1,4-benzodioxin-3-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::MLS000051826::SMR000080901::cid_2971957

SMILES C(c1nnc2sc(nn12)C1COc2ccccc2O1)n1nnc2ccccc12

InChI Key InChIKey=JWQQOJJCZPLJLG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34438   

TargetGag-Pol polyprotein(HIV-1)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34438(1-{[6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]tri...)
Affinity DataIC50: 664nMpH: 8.0 T: 2°CAssay Description:A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM34438(1-{[6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-LOX in A23187-induced human whole blood assessed as reduction in LTB4 production pre-incubated for 20 mins before A23187 additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM34438(1-{[6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]tri...)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL2-DE3 incubated 10 mins before substrate addition by fluorescence spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed