BDBM343 (3R,4S,5S,6R)-2,7-bis[(3-acetylphenyl)methyl]-4,5-dihydroxy-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepane-1,1-dione::CHEMBL340986::Cyclic Sulfamide deriv. 21

SMILES CC(=O)c1cccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3cccc(c3)C(C)=O)S2(=O)=O)c1

InChI Key InChIKey=SSKLZXDOGDJZRC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM343(CHEMBL340986 | (3R,4S,5S,6R)-2,7-bis[(3-acetylphen...)
Affinity DataKi:  59nM ΔG°:  -10.0kcal/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
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PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM343(CHEMBL340986 | (3R,4S,5S,6R)-2,7-bis[(3-acetylphen...)
Affinity DataKi:  59nMAssay Description:Inhibitory activity against HIV-1 Protease expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed