BDBM3428 1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea::6-arylpyrido[2,3-d]pyrimidine deriv. 1::CHEMBL57366::PD089828
SMILES CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl
InChI Key InChIKey=RRWSNCZYJCOEFX-UHFFFAOYSA-N
Data 19 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 3428
TargetFibroblast growth factor receptor 4(Human)
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of FGFR4 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Human)
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: 5.00E+4nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Human)
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Human)
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of FGFR2 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Human)
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of FGFR3 (unknown origin) after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Human)
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMpH: 7.4 T: 2°CAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 220nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Human)
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Health Science Center Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair