BDBM341617 1-(5-(3,4-dimethoxyphenyl)-7,8-dihydrothiazolo-[2',3':2,3]imidazo[4,5-c]pyridin-6(5H)-yl)-2-(naphthalen-2-yloxy)ethanone::US9765092, Example 6.1.1

SMILES COc1ccc(cc1OC)C1N(CCc2nc3sccn3c12)C(=O)COc1ccc2ccccc2c1

InChI Key InChIKey=BQAHNNFKOWIMJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341617   

TargetTryptophan 5-hydroxylase 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341617(US9765092, Example 6.1.1 | 1-(5-(3,4-dimethoxyphen...)
Affinity DataIC50: 4nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2019
Entry Details
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