BDBM341572 (R)-1-(5-(2,4-dimethylthiazol-5-yl)-2-methyl-7,8-dihydro-[1,3,4]thiadiazolo[2',3':2,3]imidazo[4,5-c]pyridin-6(5H)-yl)-2-((6-(1,1-dioxidoisothiazolidin-2-yl)-2-ethylpyridin-3-yl)oxy)ethanone::US9765092, Example 1.68.8

SMILES CCc1nc(ccc1OCC(=O)N1CCc2nc3sc(C)nn3c2[C@@H]1c1sc(C)nc1C)N1CCCS1(=O)=O

InChI Key InChIKey=TXXZPALKCRDUOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341572   

TargetTryptophan 5-hydroxylase 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341572(US9765092, Example 1.68.8 | (R)-1-(5-(2,4-dimethyl...)
Affinity DataIC50: 5nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
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US Patent