BDBM339794 US10202340, Example 13

SMILES COc1ccc(cc1)[C@@H](O)[C@@H](CN1CCCC1)NC(=O)CC1CCCc2ccccc12

InChI Key InChIKey=BDHUKYIAAPFAJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 339794   

TargetCeramide glucosyltransferase(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM339794(US10202340, Example 13)
Affinity DataIC50: 270nMAssay Description:Inhibition of GlcCer synthesis in broken wild-type MDCK cell preparationsMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCeramide glucosyltransferase(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM339794(US10202340, Example 13)
Affinity DataIC50: 11nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCeramide glucosyltransferase(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM339794(US10202340, Example 13)
Affinity DataIC50: 45nMAssay Description:)Inhibition of GlcCer production in MDCKII cells stably expressing human MDR1 (obtained from The Netherlands Cancer Institute).More data for this Ligand-Target Pair
In DepthDetails
US Patent