BDBM338615 N-benzyl-4-(trans-2- (((3-methyl-2-thienyl)- methyl)amino)cyclo- propyl)benzamide trifluoroacetate::US9751885, 47

SMILES Cc1ccsc1CNC1CC1c1ccc(cc1)C(=O)NCc1ccccc1

InChI Key InChIKey=UBCLLFAOAPINST-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 338615   

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338615(N-benzyl-4-(trans-2- (((3-methyl-2-thienyl)- methy...)
Affinity DataIC50: 100nMAssay Description:A test compound dissolved in 2.5% DMSO was added by 4 μL to 3 μL reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetAmine oxidase [flavin-containing] A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338615(N-benzyl-4-(trans-2- (((3-methyl-2-thienyl)- methy...)
Affinity DataIC50: 5.00E+3nMAssay Description:A test compound dissolved in 4% DMSO was added by 12.5 μL to 25 μL reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing 400 ng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetAmine oxidase [flavin-containing] B(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338615(N-benzyl-4-(trans-2- (((3-methyl-2-thienyl)- methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent