BDBM337757 3-[2-Chloro-3-(trifluoromethyl)benzyl]-2,4-dioxo-1-[4-(2-oxoimidazolidin-1-yl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 150

SMILES OC(=O)c1cn(-c2ccc(cc2)N2CCNC2=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=UQNMBJZCVNEODK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337757   

TargetChymase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337757(3-[2-Chloro-3-(trifluoromethyl)benzyl]-2,4-dioxo-1...)
Affinity DataIC50: 60nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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