BDBM337676 3-[2-Methyl-3-(trifluoromethyl)benzyl]-2,4-dioxo-1-[4-(2-oxoimidazolidin-1-yl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 51

SMILES Cc1c(cccc1C(F)(F)F)CN2C(=O)C(=CN(C2=O)c3ccc(cc3)N4CCNC4=O)C(=O)O

InChI Key InChIKey=MUZPDPKTCZSNCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337676   

TargetChymase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337676(3-[2-Methyl-3-(trifluoromethyl)benzyl]-2,4-dioxo-1...)
Affinity DataIC50: 45nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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