BDBM337415 US9745321, Compound 33

SMILES COc1ncc(cc1NS(C)(=O)=O)-c1nc(nc2c(CN3CCN(CC3)C3CCOCC3)csc12)N1CCOCC1

InChI Key InChIKey=AOTSDJWASHLBQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337415   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM337415(US9745321, Compound 33)
Affinity DataIC50: 4.20nMAssay Description:1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS.2. Compound was formulated in 100% DMSO in a concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent