BDBM335723 2,2-Dimethyl-N-((1-methyl-3- oxo-2,3-dihydroisoquinolin-4- yl)methyl)-7-(6-(piperazin-1- yl)pyridin-3-yl)-2,3- dihydrobenzofuran-5- carboxamide::US9738630, Example 17

SMILES Cc1[nH]c(=O)c(CNC(=O)c2cc3CC(C)(C)Oc3c(c2)-c2ccc(nc2)N2CCNCC2)c2ccccc12

InChI Key InChIKey=ZUSPPJRHONBPFB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335723   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335723(US9738630, Example 17 | 2,2-Dimethyl-N-((1-methyl-...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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