BDBM33437 (5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimethoxyphenyl)methanone::(5-azanyl-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimethoxyphenyl)methanone::1-(3,4-dimethoxybenzoyl)-3-phenyl-1H-1,2,4-triazol-5-amine::MLS000099650::SMR000074479::cid_975107

SMILES COc1ccc(cc1OC)C(=O)n1nc(nc1N)-c1ccccc1

InChI Key InChIKey=KJFHJZMOFADPOP-UHFFFAOYSA-N

Data  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 33437   

TargetSuppressor of tumorigenicity 14 protein(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-14(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCathepsin G(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 4.43E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetLysosomal acid glucosylceramidase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 1.92E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetKallikrein-5(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 2.12E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay