BDBM332597 (2E)-3-(4-bromophenyl)-1-(2-{[4-fluoro-2-(trifluoromethyl)phenyl]carbonyl}-2,7-diazaspiro[3.5]non-7-yl)prop-2-en-1-one::US10196369, Compound C52

SMILES Fc1ccc(C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)c(c1)C(F)(F)F

InChI Key InChIKey=PQZBFRYMNKABGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332597   

TargetG-protein coupled receptor 183(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332597(US10196369, Compound C52 | (2E)-3-(4-bromophenyl)-...)
Affinity DataIC50: 5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
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US Patent