BDBM332567 (2E)-3-(4-bromophenyl)-1-(7-{[4-fluoro-3-(trifluoromethyl)phenyl]carbonyl}-2,7-diazaspiro[3.5]non-2-yl)prop-2-en-1-one::US10196369, Compound C22

SMILES Fc1ccc(cc1C(F)(F)F)C(=O)N1CCC2(CN(C2)C(=O)\C=C\c2ccc(Br)cc2)CC1

InChI Key InChIKey=IBHIIWQDGQHLFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332567   

TargetG-protein coupled receptor 183(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332567(US10196369, Compound C22 | (2E)-3-(4-bromophenyl)-...)
Affinity DataIC50: 5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
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US Patent