BDBM33218 Adenine, 1::CHEMBL226345::purine, 6

SMILES Nc1ncnc2nc[nH]c12

InChI Key InChIKey=GFFGJBXGBJISGV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 33218   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM33218(CHEMBL226345 | Adenine, 1 | purine, 6)
Affinity DataIC50: 4.00E+6nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
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PubMed
TargetXanthine dehydrogenase/oxidase(Human)
National Institute of Pharmaceutical Education and Research

LigandPNGBDBM33218(CHEMBL226345 | Adenine, 1 | purine, 6)
Affinity DataIC50: 7.56E+4nMAssay Description:Inhibition assay of the xanthine oxidase reaction by various purine based inhibitors was measured in terms of the decrease in uric acid formation at ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM33218(CHEMBL226345 | Adenine, 1 | purine, 6)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
National Institute of Pharmaceutical Education and Research

LigandPNGBDBM33218(CHEMBL226345 | Adenine, 1 | purine, 6)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed