BDBM332139 1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-N-(2-hydroxy-ethyl)-N-methyl-spiro[1,2-dihydro-indole-3,1'-cyclopropane]-6-carboxylicacid amide::US10189854, Compound 95

SMILES CN(CCO)C(=O)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1ccccc1F

InChI Key InChIKey=VIRNZTKVBDRUGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332139   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332139(US10189854, Compound 95 | 1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
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Date in BDB:
6/12/2019
Entry Details
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