BDBM332100 3-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-indole-3,1'-cyclopropane]-1-yl]-pyrimidin-5-yl]-benzamide::US10189854, Compound 54

SMILES NC(=O)c1cccc(c1)-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1

InChI Key InChIKey=UUMJSBFCXNTFFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332100   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332100(US10189854, Compound 54 | 3-[2-[6-(Morpholine-4-ca...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent