BDBM33210 4-(7H-purin-6-yl)morpholine::purine, 9

SMILES C1CN(CCO1)c1ncnc2nc[nH]c12

InChI Key InChIKey=MEOMXKNIFWDDGZ-UHFFFAOYSA-N

Data  4 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 33210   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

LigandPNGBDBM33210(4-(7H-purin-6-yl)morpholine | purine, 9)
Affinity DatapH: 7.5 T: 2°CAssay Description:AlphaScreen (PerkinElmer Life Sciences, Inc) was performed in opaque 384-well polypropylene plates. The assay relies on hydrogel coated Donor and Acc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

LigandPNGBDBM33210(4-(7H-purin-6-yl)morpholine | purine, 9)
Affinity DataIC50: 4.20E+4nMpH: 7.5 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33210(4-(7H-purin-6-yl)morpholine | purine, 9)
Affinity DataIC50: 7.09E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSerine/threonine-protein kinase PAK 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM33210(4-(7H-purin-6-yl)morpholine | purine, 9)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PAK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM33210(4-(7H-purin-6-yl)morpholine | purine, 9)
Affinity DataIC50: 9.20E+4nMAssay Description:Competitive inhibition of PDK1 using [gamma-33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed