BDBM331282 10-Methanesulfonyl-N-methyl-5-[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-8-[(S)-oxan-4-yl(phenyl)methyl]-N-(propan-2-yl)-3,8,12-triazatricyclo[7.4.0.02,7]trideca-1(13),2::US9725449, Example 116

SMILES CC(C)N(C)c1ncc(c2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c12)-c1c(C)nnn1C)S(C)(=O)=O

InChI Key InChIKey=JPOHSHUCACMYNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331282   

LigandPNGBDBM331282(10-Methanesulfonyl-N-methyl-5-[4-(2H3)methyl-1-met...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In DepthDetails
US Patent