BDBM330445 N-[dimethyl(oxido)- lambda~4~-sulfanylidene]- 5-{4-[4-({[(2-fluoro- 5-methylphenyl)amino] carbonyl}amino)phenoxy] pyridin-2-yl}-1H-pyrrole- 3-carboxamide::US9725433, 101

SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(c3)-c3cc(c[nH]3)C(=O)N=S(C)(C)=O)cc2)c1

InChI Key InChIKey=GVMOWHZUDCJBPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330445   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM330445(N-[dimethyl(oxido)- lambda~4~-sulfanylidene]- 5-{4...)
Affinity DataIC50: 8nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
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Date in BDB:
6/12/2019
Entry Details
Go to US Patent