BDBM330229 US10301336, Comp No. 5::US9663543, Compound 5::diethyl 3-acetyl-1-(2- ((2S,3aR,6aR)-2-(3-chloro- 2- fluorobenzylcarbamoyl)hexa- hydrocyclopenta[b]pyrrol- 1(2H)-yl)-2-oxoethyl)-1H- indol-6-ylphosphonate

SMILES CCOP(=O)(OCC)c1ccc2c(cn(CC(=O)N3[C@@H]4CCC[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1)C(C)=O

InChI Key InChIKey=OHLZUNSDXBMTOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330229   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM330229(US9663543, Compound 5 | diethyl 3-acetyl-1-(2- ((2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM330229(US9663543, Compound 5 | diethyl 3-acetyl-1-(2- ((2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent