BDBM330200 1-[4-[[(1R,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]-3-[3-(trifluoromethyl)phenyl]urea::US9663530, Example 44

SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(C[C@@]34CN[C@@H](CO3)C4)cc2)c1

InChI Key InChIKey=SOIFOPJZEGZLML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330200   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330200(US9663530, Example 44 | 1-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 4.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330200(US9663530, Example 44 | 1-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 10.8nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent