BDBM330176 5-Chloro-N-[4-[(1R,4S)-5-oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]pyridin-2-amine::US9663530, Example 20

SMILES Clc1ccc(Nc2ccc(cc2)[C@@]23CN[C@@H](CO2)C3)nc1

InChI Key InChIKey=OCKNSZXCSFMCPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330176   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330176(US9663530, Example 20 | 5-Chloro-N-[4-[(1R,4S)-5-o...)
Affinity DataIC50: 6.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330176(US9663530, Example 20 | 5-Chloro-N-[4-[(1R,4S)-5-o...)
Affinity DataIC50: 1.78E+3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent