BDBM32945 (4-methyl-5-thioxo-1,2,4-triazol-1-yl)-(p-tolyl)methanone::(4-methylphenyl)-(4-methyl-5-sulfanylidene-1,2,4-triazol-1-yl)methanone::MLS001003934::SMR000347727::cid_2376254

SMILES Cc1ccc(cc1)C(=O)n1ncn(C)c1=S

InChI Key InChIKey=GHJUQPDHYJIXSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32945   

TargetProthrombin(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32945(cid_2376254 | SMR000347727 | MLS001003934 | (4-met...)
Affinity DataIC50: 1.02E+3nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32945(cid_2376254 | SMR000347727 | MLS001003934 | (4-met...)
Affinity DataIC50: 122nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32945(cid_2376254 | SMR000347727 | MLS001003934 | (4-met...)
Affinity DataIC50: 498nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay