BDBM32868 (5-amino-1-methylsulfonylpyrazol-3-yl) thiophene-2-carboxylate::(5-azanyl-1-methylsulfonyl-pyrazol-3-yl) thiophene-2-carboxylate::2-thiophenecarboxylic acid (5-amino-1-methylsulfonyl-3-pyrazolyl) ester::MLS001045541::SMR000386107::cid_3685806::thiophene-2-carboxylic acid (5-amino-1-mesyl-pyrazol-3-yl) ester

SMILES CS(=O)(=O)n1nc(OC(=O)c2cccs2)cc1N

InChI Key InChIKey=NEKUFCDAKBXJIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32868   

TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32868(SMR000386107 | (5-amino-1-methylsulfonylpyrazol-3-...)
Affinity DataIC50: 152nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32868(SMR000386107 | (5-amino-1-methylsulfonylpyrazol-3-...)
Affinity DataIC50: 2.23E+4nMAssay Description:Human liver cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease. There has been a recent resurgence of interest in cathepsin B due to research...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay