BDBM32768 2-furancarboxylic acid [2-(2-furanyl)-4-(phenyliminomethyl)-5-oxazolyl] ester::MLS000036330::SMR000041595::[2-(furan-2-yl)-4-(phenyliminomethyl)-1,3-oxazol-5-yl] furan-2-carboxylate::cid_660829::furan-2-carboxylic acid [2-(2-furyl)-4-(phenyliminomethyl)oxazol-5-yl] ester

SMILES O=C(Oc1oc(nc1\C=N\c1ccccc1)-c1ccco1)c1ccco1

InChI Key InChIKey=ZBVMFYIAGCLVCR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32768   

TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32768(SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethy...)
Affinity DataIC50: 3.85E+4nMpH: 6.8 T: 2°CAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetProthrombin(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32768(SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethy...)
Affinity DataIC50: 1.32E+3nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32768(SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethy...)
Affinity DataIC50: 6.34E+3nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32768(SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethy...)
Affinity DataIC50: 3.85E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32768(SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetProcathepsin L(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32768(SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay