BDBM32643 amino pyrimidine ketone, 3

SMILES CC1(Cc2c(c(ncn2)N)C(=O)C1)C

InChI Key InChIKey=DYPFWRCGECJCBK-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32643   

TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32643(amino pyrimidine ketone, 3)
Affinity DataIC50: 6.08E+4nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)