BDBM3256 4-(Benzylamino)quinazoline deriv. 7::N-benzylquinazolin-4-amine::benzyl(quinazolin-4-yl)amine;hydrochloride::cid_616573

SMILES C(Nc1ncnc2ccccc12)c1ccccc1

InChI Key InChIKey=FVWANTDQRFSCAL-UHFFFAOYSA-N

Data  9 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 3256   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 320nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataEC50:  3.01E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataEC50:  4.81E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataEC50:  4.27E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 1.39E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 2.19E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCOUP transcription factor 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 9.32E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCOUP transcription factor 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 1.03E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGalanin receptor type 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 1.25E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGalanin receptor type 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 2.42E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetTegument protein VP16(HHV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 8.53E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetTegument protein VP16(HHV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM3256(N-benzylquinazolin-4-amine | benzyl(quinazolin-4-y...)
Affinity DataIC50: 8.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay