BDBM32518 pyridine amide, 9

SMILES CC1CCN(CC1)C(=O)c1cccc(n1)-c1ccccc1Cl

InChI Key InChIKey=QVYHGHABFSLALV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32518   

LigandPNGBDBM32518(pyridine amide, 9)
Affinity DataIC50: 17nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM32518(pyridine amide, 9)
Affinity DataIC50: 17nMAssay Description:Inhibition of human 11-betaHSD1 by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed