BDBM324779 2-(4-(8-(2-(Trifluoromethyl)phenyl)-7,8-dihydro-6H-pyrrolo[2′,1′:2,3]imidazo[4,5-b]pyridin-2-yl)phenyl)propan-2-ol::US10189840, Example 25

SMILES CC(C)(O)c1ccc(cc1)-c1ccc2nc3CCC(c4ccccc4C(F)(F)F)n3c2n1

InChI Key InChIKey=XLDXEBXBEVPCDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324779   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM324779(2-(4-(8-(2-(Trifluoromethyl)phenyl)-7,8-dihydro-6H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
Go to US Patent