BDBM324768 2-(4-(6-Fluoro-8-(2-(trifluoromethyl)phenyl)-7,8-dihydro-6H-pyrrolo[2′,1′:2,3]imidazo[4,5-b]pyridin-2-yl)phenyl)propan-2-ol::US10189840, Example 14

SMILES CC(C)(O)c1ccc(cc1)-c1ccc2nc3C(F)CC(c4ccccc4C(F)(F)F)n3c2n1

InChI Key InChIKey=AQHQIKSWRGMNJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324768   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM324768(2-(4-(6-Fluoro-8-(2-(trifluoromethyl)phenyl)-7,8-d...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
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