BDBM324672 1'-({5-Chloro-1-[2-(thietan-3- yl)ethyl]-1H-pyrrolo[2,3-c]pyridin-2- yl}methyl)spiro[cyclopropane-1,3'- pyrrolo[2,3-c]pyridin]-2'(1'H)-one::US10189838, Example 4-10

SMILES Clc1cc2cc(CN3C(=O)C4(CC4)c4ccncc34)n(CCC3CSC3)c2cn1

InChI Key InChIKey=CNSZCCPKOXOYRF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324672   

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandPNGBDBM324672(1'-({5-Chloro-1-[2-(thietan-3- yl)ethyl]-1H-pyrrol...)
Affinity DataEC50:  74nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
Go to US Patent