BDBM323785 4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-2,3-difluorobenzoic acid::US10189788, Example 65

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)Nc1ccc(C(O)=O)c(F)c1F)-c1ccccc1

InChI Key InChIKey=MZCWGNYUXKRMQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323785   

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323785(4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbon...)
Affinity DataIC50: 105nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323785(4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbon...)
Affinity DataIC50: 60nMAssay Description:For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent