BDBM323720 US10188756, Compound CN166

SMILES ONC(=O)\C=C\c1ccc(CNCC2CCCCC2)c(F)c1

InChI Key InChIKey=NGTLBSGOPOBCFZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 323720   

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM323720(US10188756, Compound CN166)
Affinity DataIC50: 1.64nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM323720(US10188756, Compound CN166)
Affinity DataIC50: 14.2nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM323720(US10188756, Compound CN166)
Affinity DataIC50: 0.540nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM323720(US10188756, Compound CN166)
Affinity DataIC50: 11.7nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
The General Hospital

US Patent
LigandPNGBDBM323720(US10188756, Compound CN166)
Affinity DataIC50: 725nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent