BDBM323445 1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol::US10188615, Example 10::US10639286, Example 10

SMILES NCCCc1cccc(OCC2(O)CCCCC2)c1

InChI Key InChIKey=IZKQLYLRKORKAO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323445   

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandPNGBDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRetinoid isomerohydrolase(Bovine)
Acucela

US Patent
LigandPNGBDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRetinaldehyde-binding protein 1(Bovine)
Acucela

US Patent
LigandPNGBDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50: 100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRetinaldehyde-binding protein 1(Human)
Acucela

US Patent
LigandPNGBDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In DepthDetails
US Patent