BDBM323157 US9629836, 81

SMILES C[C@H](O)C(=O)N1CCC(C)(CC1)n1c(C)nc2cnc3cc(F)c(cc3c12)-c1ccc(Oc2cccn(C)c2=O)cc1Cl

InChI Key InChIKey=HGYCZOIGHPLYAJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323157   

TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Human)
Novartis

US Patent

LigandBDBM323157(US9629836, 81)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/20/2019
Entry Details
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