BDBM32281 6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine::6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine::6-(3,4-dimethoxyphenyl)-3-(2-furyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine::6-(3,4-dimethoxyphenyl)-3-(furan-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine::MLS000557008::SMR000148125::cid_937381

SMILES COc1ccc(cc1OC)C1=Nn2c(SC1)nnc2-c1ccco1

InChI Key InChIKey=AIWFEEQBDGUZIM-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32281   

LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  2.85E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  4.60E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  1.15E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-like protein 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  4.24E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetApoptosis regulator Bcl-2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  1.21E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  2.94E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay