BDBM32259 4-(6-methyl-5-imidazo[2,1-b]thiazolyl)-N-(4-methyl-2-pyridinyl)-2-thiazolamine::4-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine::MLS000034327::SMR000010233::[4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2-yl]-(4-methyl-pyridin-2-yl)-amine::[4-(6-methylimidazo[2,1-b]thiazol-5-yl)thiazol-2-yl]-(4-methyl-2-pyridyl)amine::cid_644740

SMILES Cc1nc2sccn2c1-c1csc(Nc2cc(C)ccn2)n1

InChI Key InChIKey=IFAWIELOCTZGNZ-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32259   

LigandPNGBDBM32259([4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2...)
Affinity DataEC50:  2.40E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetLysosomal acid glucosylceramidase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32259([4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2...)
Affinity DataEC50: >5.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM32259([4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2...)
Affinity DataEC50:  1.27E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-like protein 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32259([4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2...)
Affinity DataEC50:  1.57E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM32259([4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2...)
Affinity DataEC50:  1.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32259([4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2...)
Affinity DataIC50: 9.31E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay