BDBM32212 1H-indol-5-ol::cid_16054

SMILES Oc1ccc2[nH]ccc2c1

InChI Key InChIKey=LMIQERWZRIFWNZ-UHFFFAOYSA-N

Data  5 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 32212   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetLarge T antigen(SV40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 8.02E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetDNA repair and recombination protein RadA(Pyrococcus furiosus)
University of Cambridge

LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataKd:  2.10E+6nMAssay Description:The thermal-shift denaturation assay was performed on an iCycler iQ Real Time Detection System (BioRad) in 96-well iCycler iQ PCR plates sealed with ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA repair protein RAD51 homolog 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataKd:  2.10E+6nMAssay Description:Binding affinity to RAD51 (unknown origin) by isothermal calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataEC50:  1.00E+6nMAssay Description:Activity at human alpha-7 nACh receptor expressed in Xenopus laevis oocyte assessed as increase in acetylcholine-induced currentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed