BDBM32042 (4E)-3-hydroxy-4-[(6-quinolinylamino)methylidene]-1-cyclohexa-2,5-dienone::(4E)-3-hydroxy-4-[(6-quinolylamino)methylene]cyclohexa-2,5-dien-1-one::(4E)-3-hydroxy-4-[(quinolin-6-ylamino)methylidene]cyclohexa-2,5-dien-1-one::(4E)-3-oxidanyl-4-[(quinolin-6-ylamino)methylidene]cyclohexa-2,5-dien-1-one::MLS000079480::SMR000041153::cid_5389237

SMILES Oc1ccc(C=Nc2ccc3ncccc3c2)c(O)c1

InChI Key InChIKey=UOPYWJIBUUJJDQ-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 32042   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataIC50: 5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataIC50: 5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataIC50: 5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataEC50:  6.35E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32042(MLS000079480 | (4E)-3-oxidanyl-4-[(quinolin-6-ylam...)
Affinity DataEC50:  2.90E+4nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay