BDBM319932 N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- (5-methyl- 1,3-thiazol-2- yl)-5- (tetrahydro- 2H-pyran-4- ylmethoxy) benzamide::US10174016, Example 99::US10202369, Example 99::US10472354, Example 99

SMILES C[C@@H](NC(=O)c1cc(OCC2CCOCC2)cc(c1)-c1ncc(C)s1)c1ccc(C)nn1

InChI Key InChIKey=FNFCPAXHCILJLE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 319932   

TargetP2X purinoceptor 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 2nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 2nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 2nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 2nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In DepthDetails
US Patent