BDBM319622 7-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)ethyl)-6-chloro-3,4-dihydroquinolin-2(1H)-one::US10174011, Example 23

SMILES Clc1cc2CCC(=O)Nc2cc1CCN1CCN(CC1)c1cccc2sccc12

InChI Key InChIKey=HIEBSROLKYHUCT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319622   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319622(US10174011, Example 23 | 7-(2-(4-(benzo[b]thiophen...)
Affinity DataEC50:  463nMAssay Description:The 5-HT1A receptor agonism activity test (The agonism activity of test compounds on 5-HT1A receptor expressing human recombinant 5-HT1A receptor in ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319622(US10174011, Example 23 | 7-(2-(4-(benzo[b]thiophen...)
Affinity DataIC50: 81.2nMAssay Description:The D2 receptor antagonism activity test (The antagonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319622(US10174011, Example 23 | 7-(2-(4-(benzo[b]thiophen...)
Affinity DataIC50: 97.6nMAssay Description:The 5-HT2A receptor antagonism activity test (The antagonism activity of test compounds on 5-HT2A receptor expressing human recombinant 5-HT2A recept...More data for this Ligand-Target Pair
In DepthDetails
US Patent