BDBM319588 US10174007, Example 7::US10787438, Example 7::US10988463, Example 7::US11634410, Example 7

SMILES C[C@H]1[C@H](O)CN1c1nc(N2C[C@H]3[C@H](CC(O)=O)[C@H]3C2)c(C2CC2)c(n1)C(F)(F)F

InChI Key InChIKey=OLZMLWDRLUHLHZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 319588   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319588(US10174007, Example 7 | US10787438, Example 7 | US...)
Affinity DataIC50: 111nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319588(US10174007, Example 7 | US10787438, Example 7 | US...)
Affinity DataIC50: 111nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319588(US10174007, Example 7 | US10787438, Example 7 | US...)
Affinity DataIC50: 111nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM319588(US10174007, Example 7 | US10787438, Example 7 | US...)
Affinity DataIC50: 111nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent