BDBM3182 2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]azepan-4-yl}oxy)carbonyl]phenyl}carbonyl)-3-hydroxybenzoic acid::Balanol Analog 1(+/-)::CHEMBL49354

SMILES c1cc(c(c(c1)O)C(=O)c2c(cc(cc2O)C(=O)O[C@@H]3CCCNC[C@H]3NC(=O)c4ccc(cc4)O)O)C(=O)O

InChI Key InChIKey=XYUFCXJZFZPEJD-UHFFFAOYSA-N

Data  16 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 3182   

TargetProtein kinase C alpha type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 38nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMed
LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2005
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein kinase C eta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C eta isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 1 isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alpha isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C delta isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C gamma isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilon isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Sphinx Laboratories

LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2 isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM3182(CHEMBL49354 | 2-({2,6-dihydroxy-4-[({3-[(4-hydroxy...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C zeta isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed