BDBM317653 US11337976, Compound P-0024::US20230277534, Compound P-0024::US9624213, Compound P-0024

SMILES Fc1ccc(NS(=O)(=O)N2CCCC2)c(F)c1C(=O)c1c[nH]c2ncc(I)cc12

InChI Key InChIKey=ADFJPIJPWMHZRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317653   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Plexxikon

US Patent
LigandPNGBDBM317653(US9624213, Compound P-0024 | US11337976, Compound ...)
Affinity DataIC50: 100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Plexxikon

US Patent
LigandPNGBDBM317653(US9624213, Compound P-0024 | US11337976, Compound ...)
Affinity DataIC50: 100nMAssay Description:For example, the biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Plexxikon

US Patent
LigandPNGBDBM317653(US9624213, Compound P-0024 | US11337976, Compound ...)
Affinity DataIC50: 100nMAssay Description:The biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, where inhibit...More data for this Ligand-Target Pair
In DepthDetails
US Patent