BDBM317633 6-(aminomethyl)-5-(2-(dimethylamino)ethyl)-2,3-dihydropyrazolo[1,5-a]pyridin-7(1H)-one::US9624205, 2

SMILES CC(C1CCOCC1)n1c(C)c(C(=O)NCc2c(C)n(C)[nH]c2=O)c2ccccc12

InChI Key InChIKey=HIXYKJFMFAOGLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317633   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317633(US9624205, 2 | 6-(aminomethyl)-5-(2-(dimethylamino...)
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

LigandPNGBDBM317633(US9624205, 2 | 6-(aminomethyl)-5-(2-(dimethylamino...)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent